The following is a summary of “Critically ill adult patients with acute leukemia: a systematic review and meta-analysis,” published in the January 2025 issue of Critical Care by Chean et al. Researche ...
The monocytic leukemia zinc-finger protein (MOZ) gene is rearranged in t(8; 16)(p11; p13) and inv(8)(p11q13) associated with acute myeloid leukemia. The other fusion partners involved are CBP and ...
THP-1 = Human acute monocytic leukemia cell line. Disclosure: Research in Kris Chadee's laboratory is supported by grants from the Crohn's and Colitis Foundation of Canada, the Canadian Institute ...
CCR2 was highly expressed on malignant monocytes from AML patient samples, with cases of acute monocytic leukemia (M5) and acute myelomonocytic leukemia (M4), showing the highest levels of expression.