Dimerix has achieved a key milestone in its ACTION3 phase III trial of lead asset DMX-200 into focal segmental ...

Abstract We investigated the effects of angiotensin II (Ang II) type 1 receptor blockade with losartan on the renin-angiotensin-aldosterone system in hypertensive patients (supine diastolic blood ...

Led by Paul Mescal, Gladiator II follows Lucius, who is forced to enter the infamous Colosseum after his home is conquered by the emperors who now lead Rome. Mescal is joined by an all-star ...

Treatment with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers has been shown to improve many of the complications of hypertension, including left ventricular ...

This phase III trial is a randomised, double-blind, placebo-controlled study of the efficacy and safety of DMX200 in patients with FSGS who are receiving a stable dose of an angiotensin II receptor ...

Alpha-1 adrenergic receptor antagonist (α1-ARA) are well established treatment for benign prostatic hyperplasia (BPH)-associated lower urinary tract symptoms (LUTS). Since BPH and erectile dysfunction ...

2001). We further assessed the correlation between renin-angiotensin system and NF-κB activity, and identified a positive correlation between the levels of Ang II and phosphorylated NF-κB-p65, and a ...

Despite the tremendous success obtained using the current pharmacotherapy, especially angiotensin (Ang)-converting enzyme (ACE) inhibitors (ACEis) and Ang II receptor blockers (ARBs), the prevalence ...

Alternatively, suppression of angiotensin II may upregulate the angiotensin II receptor, making it more sensitive to angiotensin II. ARBs may offer more complete angiotensin II inhibition by ...