Human heart development is largely influenced by neural crest cells, which carefully regulate a key growth signal.

Catherine O'Hara's heart and organs were a mirror image of most people's. Though that is rare, congenital heart defects are fairly common.

The role of acetylcholine in the central and peripheral nervous systems is well established in adults. Cholinergic modulation of vascular functions and body fluid balance has been extensively studied.

A University of Houston pharmacology researcher and expert in cardiac development has identified a new cause of—and repair for—left ventricular non-compaction, also known as spongy heart disease. The ...

Loss-of-function in epicardial proteins called Numb Family Proteins leads to left ventricular noncompaction, or spongy heart, presenting with pediatric-onset heart failure. The loss of function is ...

Millions of people live with atrial fibrillation, a racing, uneven heartbeat that can leave you exhausted and scared. Yet it has been at least 30 years since a new drug for this common rhythm problem ...

Using a combination for spatial, single-cell transcriptomics and imaging data from 36 hearts, scientists from the KTH Royal Institute of Technology and their collaborators have come up with what they ...

Stem cells are precursors of a variety of different cells: They can turn into anything from blood to bone to muscle. Human blood stem cells, known as hematopoietic stem cells, are the forerunners of ...

Every human life begins as a cluster of cells that soon face critical decisions. Within weeks, those cells must choose their fates – some forming the nervous system, others the gut, heart, or muscle.