Membrane proteins are vital for cellular signaling, transport, and communication, making them attractive drug targets despite their challenging properties. Advances in mass spectrometry have enabled ...

The authors investigate arrestin2-mediated CCR5 endocytosis in the context of clathrin and AP2 contributions. Using an extensive set of NMR experiments, and supported by microscopy and other ...

Abstract: The stochastic resonance (SR) method enhances the weak periodic signal by transferring the noise energy to that of the weak signal, and is regarded as an excellent tool to extract weak ...

ABSTRACT: This paper addresses the existence of bursting phenomena and mixed-mode oscillations (MMOs) in a tree trunk structure subjected to external excitation, particularly when the aerodynamic drag ...

Scientists may have found a new way to help the body rebuild its own bones. The key is a receptor called GPR133, a kind of surface switch that turns on bone-forming cells. When researchers activated ...

Scientists have achieved a “striking” reversal of Alzheimer’s disease in mice by restoring the normal function of the brain's vasculature—the network of blood vessels that supplies it with oxygen and ...

A gene therapy that targets a form of retinitis pigmentosa showed a signal to improve retinal function for up to 3 years after treatment, according to a small clinical trial. The phase 2 SKYLINE trial ...

Angular 19 added support for signal inputs for custom elements, however the getter for the input return a function, which kind of makes sense since it's a signal, but it seems to make the API ...

1 St Vincent’s Institute of Medical Research, Fitzroy, VIC, Australia 2 Department of Medicine (St Vincent’s), University of Melbourne, Fitzroy, VIC, Australia T cell development and function depend ...

The Research Center for Traditional Chinese Medicine, Shanghai Institute of Infectious Diseases and Biosecurity, School of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, ...