The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...

A team has unearthed new findings about what happens during the minutes and hours after a cell divides, expanding our understanding of human biology -- and potentially leading to better medicines.

He graduated in 1964 from the University of Edinburgh with a degree in chemistry, which led to a research position studying the molecular structure of natural gums in specimens of acacia plants ...

The release of Weibel-Palade bodies allows the secretion of von Willebrand factor, P-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular ... revealed that sphingosine-1-phosphate binds ...

School of Environment and Civil Engineering, Dongguan University of Technology, Dongguan 523808, P. R. China Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab of Biomaterials, CAS Key ...

Cavendish Laboratory, Department of Physics, University of Cambridge, J. J. Thomson Avenue, Cambridge CB3 0HE, U.K. ISIS Neutron and Muon Source, STFC Rutherford Appleton Laboratory, Harwell Science ...

GLP-1 drugs work by mimicking the hormone GLP-1, resulting in weight loss, lowering hemoglobin A1c (HbA1c ... an oral GLP-1 small molecule and retatrutide, a GGG tri-agonist and some mid-stage ...

Molecular Cancer Therapeutics publishes articles on the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug ...

Capital structure is the mix of debt and equity that fund a company's operations. A judicious use of debt and equity is a key indicator of a strong balance sheet. A healthy capital structure that ...

Hemoglobin A1c is used clinically as a biomarker for the diagnosis and management of diabetes mellitus. Various methods are available to measure HbA1c and each has advantages and limitations. The ...

Central to the diagnosis and management of patients with diabetes mellitus is the measurement of hemoglobin A1c (HbA1c). Major studies have defined the therapeutic targets of HbA1c in order to reduce ...