Could viral infections play a role in Huntington's disease? Research suggests Apolipoprotein B mRNA editing catalytic ...

A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over ...

Researchers have made a major breakthrough in our understanding of Huntington's disease. This genetic disorder has long been ...

Published in Cell, the study titled, “Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease,” ...

APOBEC enzymes, which normally help fight viral infections by mutating viral DNA, cause repeat expansions and are unusually ...

New genetic research shows why some people develop deadly Huntington's disease earlier than others. The findings could lead ...

Researchers at Tufts University revealed a possible molecular mechanism explaining how the DNA repeats are broken and then expanded in the Huntington’s disease gene, pointing to a component of the ...

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death.

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time.

Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding ...