New genetic research shows why some people develop deadly Huntington's disease earlier than others. The findings could lead to better treatments.

Researchers have made a major breakthrough in our understanding of Huntington's disease. This genetic disorder has long been known to be caused .. | Genetics And Genomics ...

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately 20 years before a clinical motor diagnosis in people with Huntington's disease, ...

APOBEC enzymes, which normally help fight viral infections by mutating viral DNA, cause repeat expansions and are unusually ...

Researchers at Tufts University revealed a possible molecular mechanism explaining how the DNA repeats are broken and then expanded in the Huntington’s disease gene, pointing to a component of the ...

HD has long been a particularly vexing genetic disorder. While the variant of the huntingtin gene that causes it is inherited and present from birth, it doesn’t cause neurological symptoms until ...

Could viral infections play a role in Huntington's disease? Research suggests Apolipoprotein B mRNA editing catalytic ...

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time.

The mutation in the huntingtin (HTT) gene, which causes the incurable, dominantly inherited Huntington’s disease, was identified decades ago, following one of the most closely watched disease ...

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time ...

The disease is caused by a mutation in the gene coding for huntingtin, which causes the formation of an abnormally long and unstable form of the protein that is chopped up by cellular repair ...

This happens in parts of human DNA that are susceptible to reshaping into single stranded loops, such as some DNA segments of the huntingtin gene, which codes for a protein important for many ...