Fast track was first introduced by FDA to expedite development and review of drugs to treat serious conditions lacking any FDA-approved drug,” commented Gary S. Jacob, Ph.D., Chief Executive Officer ...

Institute of Medical Physics and Biophysics, Medical Department, University of Leipzig, Härtelstr. 16/18, D-04107 Leipzig, Germany ...

Moreover, the control compound with a truncated anchor (without butyl group) did not show plasma membrane labeling, which highlights the fact that membrane protein labeling is catalyzed by probe-lipid ...

Lipid metabolism plays a crucial role in cellular ... is activated by the SREBP chaperone SCAP. The ring finger protein 5 (RNF5), an endoplasmic reticulum-anchored E3 ubiquitin ligase, mediates the ...

Mukka Proteins, a leading manufacturer of fish meal, fish oil, and fish soluble paste, successfully raised a substantial amount of capital from anchor investors ahead of its much-anticipated ...

Lipid alterations in membrane and other cancer syndromes ... may largely depend on some research on membrane-associated E3 ligases. Some membrane-anchored proteins, for example, are difficult to ...

Specific protein-lipid interactions are critical for viral assembly. We present a molecular dynamics simulation study on the binding mechanism of the membrane targeting domain of HIV-1 Gag protein.

Prokaryotic mechanosensitive (MS) channels open by sensing the physical state of the membrane. As such, lipid-protein interactions represent the defining molecular process underlying ...