We’ve all had moments when we, for some reason, can’t remember something minor — the name of that hotel in Miami we loved, ...

Scientists have discovered key genetic factors that determine whether a T cell acts as a powerful disease fighter or enters an ineffective, exhausted state.

For San Diego researchers and the wider immunotherapy community, the atlas functions as a practical roadmap. It does not ...

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine ...

This image shows killer T cells surrounding and attacking a cancer cell. A new atlas developed by researchers at UC San Diego could make it possible to design custom T cells for immunotherapy to ...

T cells sit at the center of modern immunotherapy, yet many of the rules that govern their activation, differentiation, dysfunction (e.g., exhaustion), and ...

Alzheimer’s may destroy memory by flipping a single molecular switch that tells neurons to prune their own connections. Researchers found that both amyloid beta and inflammation converge on the same ...

Babies of every species from mouse to human rapidly forget things that happen to them-an effect called infantile amnesia.

Scientists have found that blocking microglia (specialist immune cells in the brain) prevents infant forgetting ("infantile amnesia") and improves memory in mice, suggesting that microglia may ...

When I was a high school student, my maternal grandmother was diagnosed with dementia. This became a reality after her husband died. My mom moved her into our home thinking we might be able to keep ...

Major Finding: Integration of the pre-T cell receptor’s pTɑ chain into chimeric antigen receptor (CAR) T cells potentiates antitumor efficacy. Concept: CAR T cells with pTɑ exhibit increased YBX1 ...