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Once inside the mitochondria, fatty acids are burned for energy. This process is known as fatty acid oxidation, essential for fat burning. L-Carnitine L-Tartrate is particularly effective because ...

It is known that PLIN5 interacts with ATGL; however, the protein complex through which PLIN5 anchors LDs to mitochondria is still uncharacterized. The MFN2–PLIN1 complex may be key for the maintenance ...

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2014). Myotube-derived exosomal miR-133a was found to silence Sirt1, a gene involved in muscle proliferation, mitochondrial biogenesis and fatty acid oxidation, suggesting that myotube-EVs potentially ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Fatty liver, also known as nonalcoholic fatty liver disease (NAFLD), is a condition where fat builds up in the liver. This fat when left unattended can lead to chronic inflammation inside the ...

Diabetes is a leading cause of global mortality and disability, and its economic burden is substantial. This Review focuses on type 2 diabetes, which makes up 90–95% of all diabetes cases. Type 2 ...