Frontiers10mon
Development of novel monoclonal antibodies for blocking NF-κB activation induced by CD2v protein in African swine fever virus
Rabbit anti-6× ... Heavy and light chain antibody fragments were amplified using a previously reported protocol (42) and sent to GenScript Biotech Co., Ltd. (Nanjing, China) for sequencing. The ...
Frontiers1y
Rational design of antibodies and development of a novel method for (1–3)-β-D glucan detection as an alternative to Limulus amebocyte lysate assay
They were washed and placed in 100 μL of goat anti-rabbit-HRP antibody for 30 min at 37 ... and the framework regions (FRs) and complementarity-determining regions (CDRs) in the variable region of BDG ...
Le Lézard1y
Introducing NeoMabtm: GemPharmatech's Innovative Antibody Gene Humanized Mouse Model
This strategy gives rise to a formidable model that synergizes the strengths of the mouse immune system with human-specific variable regions, making it an ideal candidate for propelling antibody ...
eLife1y
AIDS virus-neutralizing antibody induction reciprocal to a PI3K gain-of-function disease
Yamamoto and Matano provide solid evidence that a G63E/R CD8+ T-cell escape mutation in the accessory viral protein Nef may facilitate the induction of neutralizing antibody (nAb ... gp120 (gray), ...
eLife4y
Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies
Longitudinal characteristics of heavy and light chain clonal families.