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SNHG 18 is a long noncoding (LNC ... The median TFS of patients with high snoRNA expression levels was 32 months, in contrast to 144 months in the lower expression cohort (71). Furthermore, Gurvinder ...

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Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, Institute of Developmental Biology and Regenerative Medicine, College of Chemistry and Chemical Engineering, ...

Current lncRNA targeting methods include the use of small interfering RNAs (siRNA), antisense oligonucleotides (ASOs), and the CRISPR/Cas9 system, which are delivered in vivo via a variety of vectors ...

Using multiple genetic and molecular biology strategies in an in vitro system of female germ cell differentiation, the study further provides compelling evidence of a positive regulatory function of ...

Ji et al. also found that a small group of all the lncRNA peptides in the human genome appear to have changed little over the course of evolution, which strongly suggests that they have specific roles ...