Downregulation and upregulation - Wikipedia
In biochemistry, in the biological context of organisms' regulation of gene expression and production of gene products, downregulation is the process by which a cell decreases the …
Downregulation Definition & Meaning | Merriam-Webster Medical
The meaning of DOWNREGULATION is the process of reducing or suppressing a response to a stimulus; specifically : reduction in a cellular response to a molecule (as insulin) due to a …
What is the Difference Between Upregulation and Downregulation
Jun 15, 2023 · The main difference between upregulation and downregulation is that upregulation is the process of increasing cellular components such as proteins and RNA. In contrast, …
Down-regulation | definition of down-regulation by Medical ...
Development of a refractory or tolerant state consequent on repeated administration of a pharmacologically or physiologically active substance; often accompanied by an initial …
Downregulation - an overview | ScienceDirect Topics
Down-regulation is typically attributed to increased rate of internalization of bound receptor complexes. Up-regulation may include unmasking of cryptic binding sites (Rui et al., 1987) or …
Downregulation and Upregulation - an overview - ScienceDirect
Downregulation refers to the process of decreasing the total number of receptor sites present in cells or tissues, resulting in reduced responsiveness under conditions of prolonged agonist …
Down-regulation Definition and Examples - Biology Online
Jul 24, 2022 · It is the process that decreases ligand and receptor interactions or reduces the responsiveness of a cell to a stimulus following first exposure.
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